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Measures > Measure Information
Ghrelin, GLP-1, PYY
General Information
Measure Name: Ghrelin, GLP-1, PYY
Measure Type: Scale
Construct: Biomarkers - Hunger/Satiety
Primary Content Area: Nutrition
Secondary Content Area: Obesity
Brief Description: Hormones: Ghrelin, GLP1, PYY

The strength of the satiety response to a meal can be inferred from circulating levels of appetite-related ‘satiety’ hormones such as glucagon-like peptide 1 (GLP-1), cholecystokinin (CCK), peptide YY (PYY), insulin and amylin, which are thought to play a role in short-term appetite control. Ghrelin is also often measured but this is an orexigenic hormone i.e. hunger stimulating, and plays a physiological role in meal initiation. Due to the similar episodic nature of these peptides and subjective appetite sensations (e.g. hunger, fullness and satiety), they are often measured simultaneously as biomarkers of satiety.

There are a number of analysis techniques that can be employed to measure most of these peptides e.g. RIA and ELISA, and the recent development of ‘multiplexing’ techniques has allowed the measurement of a large number of peptides in a single assay. As such, these analyses are becoming more cost effective and useful in large-scale, longitudinal studies
Keywords: Appetite, Satiety, hunger, fullness
Target Population:
Mode of Administration: Who Administered: Researcher
How Administered: In-person
Other/Uncategorized/To-be-decided: Biological
Cost:
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(Last Updated: 3/19/2018 11:34:58 AM by Paul MacLean)

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