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Measures > Measure Information
Bioelectric Impedance Spectroscopy (BIS)
General Information
Measure Name: Bioelectric Impedance Spectroscopy (BIS)
Measure Type: Scale
Construct: Body Composition - FM, FFM, Visceral Fat
Primary Content Area: Obesity
Secondary Content Area: Anthropometrics
Brief Description: BIS is a noninvasive and comparatively inexpensive type of bioelectrical impedance analysis (BIA) to assess body composition that can be utilized in studies of any size or duration (1). The multisegmental, multifrequency BIS device allows for the identification of more components of bioimpedance (capacitance, resistance, etc.) than single-frequency BIA devices, and BIS measures of extracellular/intracellular resistance have been reported to be significantly correlated with intraabdominal FM measures by computed tomography scans (2). BIS is comparable to the single-frequency BIA devices in terms of subject burden and cost. BIS has also been reported to correlate better with FM than BMI and with visceral and/or intraabdominal fat (measured by MRI) than waist circumference or WHR (3). Overall, BIS has been reported to explain 80% to 90% of the variance in FM and visceral fat and 50% to 55% of the variance in intraabdominal fat by DXA and/or MRI (3,4). Despite the advantages of BIS, it has been reported to underestimate FM and overestimate FFM, especially in males (4), and BIS can be less reliable when the hydration status of FM and FFM are uncertain (e.g., in children, individuals with edema, and postbariatric surgery patients). In addition, there are multiple BIS systems available that have not been crossvalidated. It is therefore essential to always report the exact BIS system utilized.


1. Gibson A, Holmes J, Desautels R, Edmonds L, Nuudi L. Ability of new octapolar bioimpedance spectroscopy analyzers to predict 4-component-model percentage body fat in Hispanic, black, and white adults. Amer J Clin Nutr 2008;87:332-338.
2. Finch P. Intra-abdominal fat: comparison of computed tomography fat segmentation and bioimpedance spectroscopy. Malawi Med J 2017;29:155-159.
3. Thomas E, Collins A, McCarthy J, Fitzpatrick J, Durighel G, Goldston A, Bell J. Estimation of abdominal fat compartments by bioelectrical impedance: the validity of the ViScan measurement system in comparison with MRI. Eur J Clin Nutr 2010; 64:523-533.
4. Berstad P, Randby A, Ekeland G, Ulveland H. Body fat and fat-free mass measured by bioelectric impedance spectroscopy and dual-energy X-ray absorptiometry in obese and non-obese adults. Br J Nutr 2012;28:1192-1200.
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Mode of Administration: Who Administered: Researcher
How Administered: In-person
Other/Uncategorized/To-be-decided: Anthropometric
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(Last Updated: 4/5/2018 1:04:30 PM by Matt Schubert)

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