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    Measure Name: Calculated REE, TEE
    Current Description: In lieu of having direct or indirect measures of energy expenditure, there is a commonly used approach to estimate total and resting energy expenditure (TEE, REE).

REE can be acquired with the Mifflin St.-Jeor equation (1), which is best correlated (R^2 = 0.80 - 0.85) with calorimetric measures of REE (1) and superior to other less-studied or more population-specific equations (2). The following are the Mifflin St.-Jeor equations:

For males-
REE (kilocalories per day) = 10 x weight (kilograms) + 6.25 x height (centimeters) - 5 x age (years) + 5;

For females-
REE (kilocalories per day) = 10 x weight (kilograms) + 6.25 x height (centimeters) - 5 x age (years) - 161;

It should be noted that the Mifflin-St. Jeor equation may also have limitations in its generalizability. Equations for individuals who are transgender, intersex, have abnormal numbers of X or Y chromosomes, or who have undergone or are undergoing surgical or hormonal
therapy relevant to gender have not as yet been derived (3).

An estimate of TEE can then be obtained after a questionnaire-based assessment of Physical Activity Level (PAL) is acquired (4). PAL is defined as TEE/REE. The PAL questionnaire is simple and has been validated by correlations with PAL measured by calorimetry. It has been considered applicable across multiple studies. This questionnaire provides a self-evaluation of physical activity during work and leisure activities. The calculated REE and PAL can then be used to derive a calculated TEE.


1. Mifflin M, St. Jeor S, Hill L, Scott B, Daugherty S, Koh Y. A new predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr 1990;51:241-247.
2. Schusdziarra V, Wolfschlager K, Hausmann M, Wagenpfell S, Erdman J. Accuracy of resting energy expenditure calculations in unselected overweight and obese patients. Ann Nutr Metab 2014;65:299-309.
3. Valencak T, Osterrieder A, Schulz T. Sex matters: the effects of biological sex on adipose tissue biology and energy metabolism. Redox Biol 2017;12:806-813.
4. Johansson G, Westerterp K. Assessment of the physical activity level with two questions: validation with doubly labeled water. Int J Obes 2008;32:1031-1033.
DateFull NameAction
3/16/2018 3:08:23 PMPaul MacLean View
2/5/2018 12:14:59 PMTanya Agurs-Collins View
3/28/2017 5:41:44 PMPaul MacLean View
3/28/2017 5:41:39 PMPaul MacLean View
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